Clinical practice is shaped by international guidelines that rely on randomised trials to inform recommendations where possible. However, a key challenge is the under-representation of women, both as participants and investigators, in the majority of these trials.¹ Figure 1, reproduced from Burgess et al,²...

Cardiovascular disease (CVD) is at endemic levels worldwide and is currently the leading cause of death among both men and women. Heart attacks in women account for one-third of deaths globally.¹ In this modern age of medicine, women have worse outcomes and a higher mortality risk than men. This multifactorial...

Any discussion on lipids generally comes down to one question: “Do I need to start a lipid-lowering therapy to lower my patient’s risk of a cardiovascular event?”

Lifestyle measures are recommended for all patients, and if a secondary cause is identified for elevated lipids that should be addressed first....

Case study 1

Mr G felt fine when he went to bed at 0130, but his wife awakes at 0345 to find him struggling to get out of bed, unable to move his right arm or leg, and unable to speak. She calls 999 and he arrives at the hospital at 0430

On assessment, his right-sided weakness has now resolved, but he is...

Introduction

Amyloidosis is a disorder of protein folding, where structurally diverse precursor proteins adopt an abnormal but common fibrillar structure, ultimately damaging tissue structure and leading to organ dysfunction. Depending on the dominantly affected organ, a patient may be referred on to a...